Measurement of Atropisomer Racemization Kinetics Using Segmented Flow Technology

par Davoren, Jennifer E., Bundesmann, Mark W., Yan, Qi T., Collantes, Elizabeth M., Mente, Scot, Nason, Deane M., Gray, David L.
Publié 2012

Quick Building Blocks (QBB): An Innovative and Efficient Business Model To Speed Medicinal Chemistry Analog Synthesis

par Helal, Christopher J., Bundesmann, Mark, Hammond, Susan, Holmstrom, Melissa, Klug-McLeod, Jacquelyn, Lefker, Bruce A., McLeod, Dale, Subramanyam, Chakrapani, Zakaryants, Oleg, Sakata, Sylvie
Publié dans ACS Med Chem Lett (2019)

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

par Brodney, Michael A., Beck, Elizabeth M., Butler, Christopher R., Barreiro, Gabriela, Johnson, Eric F., Riddell, David, Parris, Kevin, Nolan, Charles E., Fan, Ying, Atchison, Kevin, Gonzales, Cathleen, Robshaw, Ashley E., Doran, Shawn D., Bundesmann, Mark W., Buzon, Leanne, Dutra, Jason, Henegar, Kevin, LaChapelle, Erik, Hou, Xinjun, Rogers, Bruce N., Pandit, Jayvardhan, Lira, Ricardo, Martinez-Alsina, Luis, Mikochik, Peter, Murray, John C., Ogilvie, Kevin, Price, Loren, Sakya, Subas M., Yu, Aijia, Zhang, Yong, O’Neill, Brian T.
Publié dans J Med Chem (2015)