Cross-Reactive Human IgM-Derived Monoclonal Antibodies that Bind to HIV-1 Envelope Glycoproteins

Por Barton F. Haynes, Dimiter S. Dimitrov, Huaxin Liao, Gerald V. Quinnan, Christopher C. Broder, Zhongyu Zhu, Weizao Chen
Publicado em 2010-02-01

Subordinate Effect of -21M HLA-B Dimorphism on NK Cell Repertoire Diversity and Function in HIV-1 Infected Individuals of African Origin

Por Elia Moreno Cubero, Ane Ogbe, Isabela Pedroza-Pacheco, Myron S. Cohen, Barton F. Haynes, Persephone Borrow, Dimitra Peppa, Dimitra Peppa
Publicado em 2020-02-01

Correlation Between Anti-gp41 Antibodies and Virus Infectivity Decay During Primary HIV-1 Infection

Por Naveen K. Vaidya, Ruy M. Ribeiro, Ruy M. Ribeiro, Pinghuang Liu, Barton F. Haynes, Georgia D. Tomaras, Alan S. Perelson
Publicado em 2018-06-01

Parallel Induction of CH505 B Cell Ontogeny-Guided Neutralizing Antibodies and tHIVconsvX Conserved Mosaic-Specific T Cells against HIV-1

Por Edmund G. Wee, Nathifa A. Moyo, Kevin O. Saunders, Celia LaBranche, Filippo Donati, Silvia Capucci, Robert Parks, Nicola Borthwick, Zara Hannoun, David C. Montefiori, Barton F. Haynes, Tomáš Hanke
Publicado em 2022-06-01

Structure and Diversity of the Rhesus Macaque Immunoglobulin Loci through Multiple De Novo Genome Assemblies

Por Akshaya Ramesh, Sam Darko, Axin Hua, Glenn Overman, Amy Ransier, Joseph R. Francica, Ashley Trama, Georgia D. Tomaras, Barton F. Haynes, Daniel C. Douek, Thomas B. Kepler, Thomas B. Kepler
Publicado em 2017-10-01

Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies.

Por Ben-Jiang Ma, S Munir Alam, Eden P Go, Xiaozhi Lu, Heather Desaire, Georgia D Tomaras, Cindy Bowman, Laura L Sutherland, Richard M Scearce, Sampa Santra, Norman L Letvin, Thomas B Kepler, Hua-Xin Liao, Barton F Haynes
Publicado em 2011-09-01

Genetic signatures in the envelope glycoproteins of HIV-1 that associate with broadly neutralizing antibodies.

Por S Gnanakaran, Marcus G Daniels, Tanmoy Bhattacharya, Alan S Lapedes, Anurag Sethi, Ming Li, Haili Tang, Kelli Greene, Hongmei Gao, Barton F Haynes, Myron S Cohen, George M Shaw, Michael S Seaman, Amit Kumar, Feng Gao, David C Montefiori, Bette Korber
Publicado em 2010-01-01

Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa.

Por Carlo Zambonelli, Antu K Dey, Susan Hilt, Samuel Stephenson, Eden P Go, Daniel F Clark, Mark Wininger, Celia Labranche, David Montefiori, Hua-Xin Liao, Ronald I Swanstrom, Heather Desaire, Barton F Haynes, Andrea Carfi, Susan W Barnett
Publicado em 2016-01-01

Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses.

Por Matthew Zirui Tay, Pinghuang Liu, LaTonya D Williams, Michael D McRaven, Sheetal Sawant, Thaddeus C Gurley, Thomas T Xu, S Moses Dennison, Hua-Xin Liao, Agnès-Laurence Chenine, S Munir Alam, M Anthony Moody, Thomas J Hope, Barton F Haynes, Georgia D Tomaras
Publicado em 2016-08-01

Pre-clinical development of a recombinant, replication-competent adenovirus serotype 4 vector vaccine expressing HIV-1 envelope 1086 clade C.

Por Jeff Alexander, Jason Mendy, Lo Vang, Jenny B Avanzini, Fermin Garduno, Darly J Manayani, Glenn Ishioka, Peggy Farness, Li-Hua Ping, Ronald Swanstrom, Robert Parks, Hua-Xin Liao, Barton F Haynes, David C Montefiori, Celia LaBranche, Jonathan Smith, Marc Gurwith, Tim Mayall
Publicado em 2013-01-01

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8.

Por Cinque Soto, Gilad Ofek, M Gordon Joyce, Baoshan Zhang, Krisha McKee, Nancy S Longo, Yongping Yang, Jinghe Huang, Robert Parks, Joshua Eudailey, Krissey E Lloyd, S Munir Alam, Barton F Haynes, NISC Comparative Sequencing Program, James C Mullikin, Mark Connors, John R Mascola, Lawrence Shapiro, Peter D Kwong
Publicado em 2016-01-01

A critical role for CD8 T cells in a nonhuman primate model of tuberculosis.

Por Crystal Y Chen, Dan Huang, Richard C Wang, Ling Shen, Gucheng Zeng, Shuyun Yao, Yun Shen, Lisa Halliday, Jeff Fortman, Milton McAllister, Jim Estep, Robert Hunt, Daphne Vasconcelos, George Du, Steven A Porcelli, Michelle H Larsen, William R Jacobs, Barton F Haynes, Norman L Letvin, Zheng W Chen
Publicado em 2009-04-01

Induction of antibodies in rhesus macaques that recognize a fusion-intermediate conformation of HIV-1 gp41.

Por S Moses Dennison, Laura L Sutherland, Frederick H Jaeger, Kara M Anasti, Robert Parks, Shelley Stewart, Cindy Bowman, Shi-Mao Xia, Ruijun Zhang, Xiaoying Shen, Richard M Scearce, Gilad Ofek, Yongping Yang, Peter D Kwong, Sampa Santra, Hua-Xin Liao, Georgia Tomaras, Norman L Letvin, Bing Chen, S Munir Alam, Barton F Haynes
Publicado em 2011-01-01

HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies.

Por Celia C LaBranche, Andrew T McGuire, Matthew D Gray, Shay Behrens, Peter D Kwong, Xuejun Chen, Tongqing Zhou, Quentin J Sattentau, James Peacock, Amanda Eaton, Kelli Greene, Hongmei Gao, Haili Tang, Lautaro G Perez, Xuejun Chen, Kevin O Saunders, Peter D Kwong, John R Mascola, Barton F Haynes, Leonidas Stamatatos, David C Montefiori
Publicado em 2018-11-01

Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting.

Por Nicole A Doria-Rose, Han R Altae-Tran, Ryan S Roark, Stephen D Schmidt, Matthew S Sutton, Mark K Louder, Gwo-Yu Chuang, Robert T Bailer, Valerie Cortez, Rui Kong, Krisha McKee, Sijy O'Dell, Felicia Wang, Salim S Abdool Karim, James M Binley, Mark Connors, Barton F Haynes, Malcolm A Martin, David C Montefiori, Lynn Morris, Julie Overbaugh, Peter D Kwong, John R Mascola, Ivelin S Georgiev
Publicado em 2017-01-01

The characterization of twenty sequenced human genomes.

Por Kimberly Pelak, Kevin V Shianna, Dongliang Ge, Jessica M Maia, Mingfu Zhu, Jason P Smith, Elizabeth T Cirulli, Jacques Fellay, Samuel P Dickson, Curtis E Gumbs, Erin L Heinzen, Anna C Need, Elizabeth K Ruzzo, Abanish Singh, C Ryan Campbell, Linda K Hong, Katharina A Lornsen, Alexander M McKenzie, Nara L M Sobreira, Julie E Hoover-Fong, Joshua D Milner, Ruth Ottman, Barton F Haynes, James J Goedert, David B Goldstein
Publicado em 2010-09-01

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.

Por Sampa Santra, Georgia D Tomaras, Ranjit Warrier, Nathan I Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, S Munir Alam, Ruijun Zhang, Sarah L Cocklin, Xiaoying Shen, Ryan Duffy, Shi-Mao Xia, Robert J Schutte, Charles W Pemble Iv, S Moses Dennison, Hui Li, Andrew Chao, Kora Vidnovic, Abbey Evans, Katja Klein, Amit Kumar, James Robinson, Gary Landucci, Donald N Forthal, David C Montefiori, Jaranit Kaewkungwal, Sorachai Nitayaphan, Punnee Pitisuttithum, Supachai Rerks-Ngarm, Merlin L Robb, Nelson L Michael, Jerome H Kim, Kelly A Soderberg, Elena E Giorgi, Lily Blair, Bette T Korber, Christiane Moog, Robin J Shattock, Norman L Letvin, Joern E Schmitz, M A Moody, Feng Gao, Guido Ferrari, George M Shaw, Barton F Haynes
Publicado em 2015-08-01