Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors

Autor Burger, Matthew T., Knapp, Mark, Wagman, Allan, Ni, Zhi-Jie, Hendrickson, Thomas, Atallah, Gordana, Zhang, Yanchen, Frazier, Kelly, Verhagen, Joelle, Pfister, Keith, Ng, Simon, Smith, Aaron, Bartulis, Sarah, Merrit, Hanne, Weismann, Marion, Xin, Xiaohua, Haznedar, Joshua, Voliva, Charles F., Iwanowicz, Ed, Pecchi, Sabina
Vydáno 2010

Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors

Autor Burger, Matthew T., Han, Wooseok, Lan, Jiong, Nishiguchi, Gisele, Bellamacina, Cornelia, Lindval, Mika, Atallah, Gordana, Ding, Yu, Mathur, Michelle, McBride, Chris, Beans, Elizabeth L., Muller, Kristine, Tamez, Victoriano, Zhang, Yanchen, Huh, Kay, Feucht, Paul, Zavorotinskaya, Tatiana, Dai, Yumin, Holash, Jocelyn, Castillo, Joseph, Langowski, John, Wang, Yingyun, Chen, Min Y., Garcia, Pablo D.
Vydáno 2013

Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer

Autor Burger, Matthew T., Pecchi, Sabina, Wagman, Allan, Ni, Zhi-Jie, Knapp, Mark, Hendrickson, Thomas, Atallah, Gordana, Pfister, Keith, Zhang, Yanchen, Bartulis, Sarah, Frazier, Kelly, Ng, Simon, Smith, Aaron, Verhagen, Joelle, Haznedar, Joshua, Huh, Kay, Iwanowicz, Ed, Xin, Xiaohua, Menezes, Daniel, Merritt, Hanne, Lee, Isabelle, Wiesmann, Marion, Kaufman, Susan, Crawford, Kenneth, Chin, Michael, Bussiere, Dirksen, Shoemaker, Kevin, Zaror, Isabel, Maira, Sauveur-Michel, Voliva, Charles F.
Vydáno 2011