Synthesis, Docking and Biological Evaluation of a Novel Class of Imidazothiazoles as IDO1 Inhibitors

por Serafini, Marta, Torre, Enza, Aprile, Silvio, Massarotti, Alberto, Fallarini, Silvia, Pirali, Tracey
Publicado en Molecules (2019)

Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors

por Aprile, Silvio, Galli, Ubaldina, Tron, Gian Cesare, Del Grosso, Erika, Travelli, Cristina, Grosa, Giorgio
Publicado en Data Brief (2019)

Biological effects of combined resveratrol and vitamin D3 on ovarian tissue

por Uberti, Francesca, Morsanuto, Vera, Aprile, Silvio, Ghirlanda, Sabrina, Stoppa, Ian, Cochis, Andrea, Grosa, Giorgio, Rimondini, Lia, Molinari, Claudio
Publicado en J Ovarian Res (2017)

1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry

por Aprile, Silvio, Riva, Beatrice, Bhela, Irene Preet, Cordero-Sanchez, Celia, Avino, Giulia, Genazzani, Armando A., Serafini, Marta, Pirali, Tracey
Publicado en ACS Med Chem Lett (2021)

Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors

por Serafini, Marta, Cordero-Sanchez, Celia, Di Paola, Rosanna, Bhela, Irene P., Aprile, Silvio, Purghè, Beatrice, Fusco, Roberta, Cuzzocrea, Salvatore, Genazzani, Armando A., Riva, Beatrice, Pirali, Tracey
Publicado en J Med Chem (2020)

Identification of a Potent Phosphoinositide 3‐Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs

por Pirali, Tracey, Ciraolo, Elisa, Aprile, Silvio, Massarotti, Alberto, Berndt, Alex, Griglio, Alessia, Serafini, Marta, Mercalli, Valentina, Landoni, Clarissa, Campa, Carlo Cosimo, Margaria, Jean Piero, Silva, Rangel L., Grosa, Giorgio, Sorba, Giovanni, Williams, Roger, Hirsch, Emilio, Tron, Gian Cesare
Publicado en ChemMedChem (2017)

Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis

por Campa, Carlo C., Silva, Rangel L., Margaria, Jean P., Pirali, Tracey, Mattos, Matheus S., Kraemer, Lucas R., Reis, Diego C., Grosa, Giorgio, Copperi, Francesca, Dalmarco, Eduardo M., Lima-Júnior, Roberto C. P., Aprile, Silvio, Sala, Valentina, Dal Bello, Federica, Prado, Douglas Silva, Alves-Filho, Jose Carlos, Medana, Claudio, Cassali, Geovanni D., Tron, Gian Cesare, Teixeira, Mauro M., Ciraolo, Elisa, Russo, Remo C., Hirsch, Emilio
Publicado en Nat Commun (2018)