Cytosolic RNA:DNA hybrids activate the cGAS–STING axis

por Mankan, Arun K, Schmidt, Tobias, Chauhan, Dhruv, Goldeck, Marion, Höning, Klara, Gaidt, Moritz, Kubarenko, Andrew V, Andreeva, Liudmila, Hopfner, Karl-Peter, Hornung, Veit
Publicado en EMBO J (2014)

Structural mechanism for NEK7-licensed NLRP3 inflammasome activation

por Sharif, Humayun, Wang, Li, Wang, Wei Li, Magupalli, Venkat Giri, Andreeva, Liudmila, Qiao, Qi, Hauenstein, Arthur V., Wu, Zhaolong, Nunez, Gabriel, Mao, Youdong, Wu, Hao
Publicado en Nature (2019)

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

por Herzner, Anna-Maria, Hagmann, Cristina Amparo, Goldeck, Marion, Wolter, Steven, Kübler, Kirsten, Wittmann, Sabine, Gramberg, Thomas, Andreeva, Liudmila, Hopfner, Karl-Peter, Mertens, Christina, Zillinger, Thomas, Jin, Tengchuan, Xiao, Tsan Sam, Bartok, Eva, Coch, Christoph, Ackermann, Damian, Hornung, Veit, Ludwig, Janos, Barchet, Winfried, Hartmann, Gunther, Schlee, Martin
Publicado en Nat Immunol (2015)