Cytosolic RNA:DNA hybrids activate the cGAS–STING axis

par Mankan, Arun K, Schmidt, Tobias, Chauhan, Dhruv, Goldeck, Marion, Höning, Klara, Gaidt, Moritz, Kubarenko, Andrew V, Andreeva, Liudmila, Hopfner, Karl-Peter, Hornung, Veit
Publié dans EMBO J (2014)

Structural mechanism for NEK7-licensed NLRP3 inflammasome activation

par Sharif, Humayun, Wang, Li, Wang, Wei Li, Magupalli, Venkat Giri, Andreeva, Liudmila, Qiao, Qi, Hauenstein, Arthur V., Wu, Zhaolong, Nunez, Gabriel, Mao, Youdong, Wu, Hao
Publié dans Nature (2019)

Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA

par Herzner, Anna-Maria, Hagmann, Cristina Amparo, Goldeck, Marion, Wolter, Steven, Kübler, Kirsten, Wittmann, Sabine, Gramberg, Thomas, Andreeva, Liudmila, Hopfner, Karl-Peter, Mertens, Christina, Zillinger, Thomas, Jin, Tengchuan, Xiao, Tsan Sam, Bartok, Eva, Coch, Christoph, Ackermann, Damian, Hornung, Veit, Ludwig, Janos, Barchet, Winfried, Hartmann, Gunther, Schlee, Martin
Publié dans Nat Immunol (2015)