Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease

por Abuznait, Alaa H., Kaddoumi, Amal
Publicado 2012

Exposure of LS-180 Cells to Drugs of Diverse Physicochemical and Therapeutic Properties Up-regulates P-glycoprotein Expression and Activity

por Abuznait, Alaa H., Patrick, Shawn G., Kaddoumi, Amal
Publicado 2011

Sustained Release Tablets Containing Soluble Polymethacrylates: Comparison with Tableted Polymethacrylate IPEC Polymers

por Obeidat, Wasfy M., Abuznait, Alaa H., Sallam, Al-Sayed A.
Publicado 2010

Enhanced Brain Amyloid-β Clearance by Rifampicin and Caffeine as a Possible Protective Mechanism Against Alzheimer’s Disease

por Qosa, Hisham, Abuznait, Alaa H., Hill, Ronald A., Kaddoumi, Amal
Publicado 2012

Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease

por Abuznait, Alaa H., Cain, Courtney, Ingram, Drury, Burk, David, Kaddoumi, Amal
Publicado 2011

Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies

por Abuznait, Alaa H., Qosa, Hisham, Busnena, Belnaser A., El Sayed, Khalid A., Kaddoumi, Amal
Publicado 2013

Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions

por Alam, Khondoker, Pahwa, Sonia, Wang, Xueying, Zhang, Pengyue, Ding, Kai, Abuznait, Alaa H., Li, Lang, Yue, Wei
Publicado en Mol Pharm (2016)

Induction of Expression and Functional Activity of P-glycoprotein Efflux Transporter by Bioactive Plant Natural Products

por Abuznait, Alaa H., Qosa, Hisham, O’Connell, Nicholas D., Akbarian-Tefaghi, Jessica, Sylvester, Paul W., El Sayed, Khalid A., Kaddoumi, Amal
Publicado 2011

Masitinib Antagonizes ATP-Binding Cassette Subfamily C Member 10-Mediated Paclitaxel Resistance: A Preclinical Study

por Kathawala, Rishil J., Sodani, Kamlesh, Chen, Kang, Patel, Atish, Abuznait, Alaa H., Anreddy, Nagaraju, Sun, Yue-Li, Kaddoumi, Amal, Ashby, Charles R., Chen, Zhe-Sheng
Publicado 2014

Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft models

por Tiwari, Amit K., Sodani, Kamlesh, Dai, Chun-ling, Abuznait, Alaa H., Singh, Satyakam, Xiao, Zhi-Jie, Patel, Atish, Talele, Tanaji T., Fu, Liwu, Kaddoumi, Amal, Gallo, James M., Chen, Zhe-Sheng
Publicado 2012