Ten Years of Tau-Targeted Immunotherapy: The Path Walked and the Roads Ahead

Por Novak, Petr, Kontsekova, Eva, Zilka, Norbert, Novak, Michal
Publicado no Front Neurosci (2018)

First-in-man tau vaccine targeting structural determinants essential for pathological tau–tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheim...

Por Kontsekova, Eva, Zilka, Norbert, Kovacech, Branislav, Novak, Petr, Novak, Michal
Publicado no Alzheimers Res Ther (2014)

Identification of structural determinants on tau protein essential for its pathological function: novel therapeutic target for tau immunotherapy in Alzheimer’s disease

Por Kontsekova, Eva, Zilka, Norbert, Kovacech, Branislav, Skrabana, Rostislav, Novak, Michal
Publicado no Alzheimers Res Ther (2014)

Functional Blockade of Tyrosine Kinase A in the Rat Basal Forebrain by a Novel Antagonistic Anti-Receptor Monoclonal Antibody

Por Cattaneo, Antonino, Capsoni, Simona, Margotti, Elisa, Righi, Massimo, Kontsekova, Eva, Pavlik, Peter, Filipcik, Peter, Novak, Michal
Publicado no J Neurosci (1999)

Therapeutic antibody targeting microtubule-binding domain prevents neuronal internalization of extracellular tau via masking neuron surface proteoglycans

Por Weisová, Petronela, Cehlár, Ondrej, Škrabana, Rostislav, Žilková, Monika, Filipčík, Peter, Kováčech, Branislav, Prčina, Michal, Wojčiaková, Ľubica, Fialová, Ľubica, Smolek, Tomáš, Kontseková, Eva, Žilka, Norbert, Novák, Michal
Publicado no Acta Neuropathol Commun (2019)

A walk through tau therapeutic strategies

Por Jadhav, Santosh, Avila, Jesus, Schöll, Michael, Kovacs, Gabor G., Kövari, Enikö, Skrabana, Rostislav, Evans, Lewis D, Kontsekova, Eva, Malawska, Barbara, de Silva, Rohan, Buee, Luc, Zilka, Norbert
Publicado no Acta Neuropathol Commun (2019)

FUNDAMANT: an interventional 72-week phase 1 follow-up study of AADvac1, an active immunotherapy against tau protein pathology in Alzheimer’s disease

Por Novak, Petr, Schmidt, Reinhold, Kontsekova, Eva, Kovacech, Branislav, Smolek, Tomas, Katina, Stanislav, Fialova, Lubica, Prcina, Michal, Parrak, Vojtech, Dal-Bianco, Peter, Brunner, Martin, Staffen, Wolfgang, Rainer, Michael, Ondrus, Matej, Ropele, Stefan, Smisek, Miroslav, Sivak, Roman, Zilka, Norbert, Winblad, Bengt, Novak, Michal
Publicado no Alzheimers Res Ther (2018)