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21
“... at the evaluation of analgesic compounds using MESH terms in PubMed. Publications were selected, which focused on (1...”
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22
“... models for neuropathic and cancer pain. EMA401 was selected as the lead compound, based on high...”
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23
“... of chronic pain and have also opened new possible therapeutic approaches, such as the development of opioid...”
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24
Por Jean, Yen-Hsuan, Chen, Wu-Fu, Sung, Chun-Sung, Duh, Chang-Yih, Huang, Shi-Ying, Lin, Chan-Shing, Tai, Ming-Hon, Tzeng, Shun-Fen, Wen, Zhi-Hong
Publicado em 2009
“... may serve as a useful lead compound in the search for new therapeutic agents for treatment...”Publicado em 2009
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25
“...)3 channels) expressed in HEK 293 cells and native mouse T-type I(Ca) were examined using standard...”
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26
“... of addiction, withdrawal and questionable efficacy for all types of pain, these compounds are far from a...”
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27
Por Ahmadi, Abbas, Khalili, Mohsen, Hajikhani, Ramin, Barghi, Leila, Mihandoust, Farnaz
Publicado em 2010
“...)] piperidine, PCP-OCH(3)-tetralyl, III) was synthesized and the acute thermal pain of this compound...”Publicado em 2010
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28
“...Esterom(®), a new drug currently in human clinical trials, is a mixture of compounds in a propylene...”
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29
“... compound at baseline and after 40 days. The measures were repeated at three and six months. The data...”
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30
Por Utreras, Elias, Terse, Anita, Keller, Jason, Iadarola, Michael J, Kulkarni, Ashok B
Publicado em 2011
“... whether resveratrol, a polyphenolic compound with known analgesic activity, can regulate Cdk5/p35 activity...”Publicado em 2011
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31
Por Wang, Xiaojuan, Liu, Jiabao, Pandey, Pankaj, Chen, Jiabao, Fronczek, Frank R., Parnham, Stuart, Qi, Xinzhu, Doerksen, Robert J., Ferreira, Daneel, Sun, Hua, Li, Shuai, Hamann, Mark T.
Publicado no Biochim Biophys Acta (2017)
“.... Their roots and stems are traditionally used to treat blood diseases and pain. The main bioactive constituents...”Publicado no Biochim Biophys Acta (2017)
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32
“... on T-type calcium channels and discuss novel compounds that are being investigated as new treatments...”
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33
Por Abdullah, Jafri Malin
Publicado em 2011
“... of Mitragyna speciosa Korth (ketum) as a tea supplement. Centella asiatica and Myristica fragrans are used...”Publicado em 2011
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34
Por Keenan, C M, Storr, M A, Thakur, G A, Wood, J T, Wager-Miller, J, Straiker, A, Eno, M R, Nikas, S P, Bashashati, M, Hu, H, Mackie, K, Makriyannis, A, Sharkey, K A
Publicado no Br J Pharmacol (2015)
“... therapeutic agents for the treatment of pain, metabolic conditions and gastrointestinal (GI) disorders...”Publicado no Br J Pharmacol (2015)
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35
Por Asenate A. X. Adrião, Aline O. dos Santos, Emilly J. S. P. de Lima, Jéssica B. Maciel, Weider H. P. Paz, Felipe M. A. da Silva, Felipe M. A. da Silva, Manuela B. Pucca, Ana M. Moura-da-Silva, Ana M. Moura-da-Silva, Wuelton M. Monteiro, Marco A. Sartim, Marco A. Sartim, Marco A. Sartim, Hector H. F. Koolen, Hector H. F. Koolen, Hector H. F. Koolen
Publicado em 2022-05-01
Assuntos:
“...bioactive compounds...”Publicado em 2022-05-01
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36
Por Knobloch, M., Portier, C.J., Levionnois, O.L., Theurillat, R., Thormann, W., Spadavecchia, C., Mevissen, M.
Publicado em 2006
“... medicine. Recently, it gained new interest for use in long-term pain therapy administered in sub-anesthetic...”Publicado em 2006
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37
Por Marshall, Kara L., Clary, Rachel C., Baba, Yoshichika, Orlowsky, Rachel L., Gerling, Gregory J., Lumpkin, Ellen A.
Publicado no Cell Rep (2016)
“...Sensory tissues exposed to the environment, such as skin, olfactory epithelia and taste buds...”Publicado no Cell Rep (2016)
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38
Por Sunder A, Shyam, Dhulipala, Satyavati, Thota, Sreekanth, Yerra, Rajeshwar, Balzarini, Jan, De Clercq, Erik
Publicado em 2013
“...BACKGROUND: From the thousands of years, metal compounds have been used in medicine for treatment...”Publicado em 2013
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39
Por Campos, Fabiana V., Menezes, Thiago N., Malacarne, Pedro F., Costa, Fábio L. S., Naumann, Gustavo B., Gomes, Helena L., Figueiredo, Suely G.
Publicado no J Venom Anim Toxins Incl Trop Dis (2016)
“... hazardous, provoking extreme pain and imposing significant socioeconomic costs, as the victims may require...”Publicado no J Venom Anim Toxins Incl Trop Dis (2016)
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40
Por Schumacher, Mark A.
Publicado em 2010
“... of the capsaicin receptor (TRPV1), the search for ‘new’ analgesics has returned to compounds used by physicians...”Publicado em 2010
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