Interleukin-4 and Interleukin-10 Are Involved in Host Resistance to Staphylococcus aureus Infection through Regulation of Gamma Interferon

Our previous study showed that gamma interferon (IFN-γ), a T-helper 1 (Th1)-type cytokine, plays a detrimental role in Staphylococcus aureus infection in mice. In this study, the role of Th2-type cytokines such as interleukin-4 (IL-4) and IL-10 in S. aureus infection was investigated. IL-10 mRNA was...

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Main Authors: Sasaki, Sanae, Nishikawa, Shinsuke, Miura, Tomisato, Mizuki, Mayuko, Yamada, Kyogo, Madarame, Hiroo, Tagawa, Yoh-Ichi, Iwakura, Yoichiro, Nakane, Akio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97441/
https://ncbi.nlm.nih.gov/pubmed/10768926
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