High-Level Expression of Plasmodium vivax Apical Membrane Antigen 1 (AMA-1) in Pichia pastoris: Strong Immunogenicity in Macaca mulatta Immunized with P. vivax AMA-1 and Adjuvant SBAS2

The apical membrane antigen 1 (AMA-1) family is a promising family of malaria blood-stage vaccine candidates that have induced protection in rodent and nonhuman primate models of malaria. Correct conformation of the protein appears to be essential for the induction of parasite-inhibitory responses,...

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Bibliographic Details
Main Authors: Kocken, Clemens H. M., Dubbeld, Martin A., Van Der Wel, Annemarie, Pronk, Jack T., Waters, Andrew P., Langermans, Jan A. M., Thomas, Alan W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC96275/
https://ncbi.nlm.nih.gov/pubmed/9864194
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