Subtype-Specific Translocation of the δ Subtype of Protein Kinase C and Its Activation by Tyrosine Phosphorylation Induced by Ceramide in HeLa Cells

We investigated the functional roles of ceramide, an intracellular lipid mediator, in cell signaling pathways by monitoring the intracellular movement of protein kinase C (PKC) subtypes fused to green fluorescent protein (GFP) in HeLa living cells. C(2)-ceramide but not C(2)-dihydroceramide induced...

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Detalhes bibliográficos
Main Authors: Kajimoto, Taketoshi, Ohmori, Shiho, Shirai, Yasuhito, Sakai, Norio, Saito, Naoaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86731/
https://ncbi.nlm.nih.gov/pubmed/11238914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1769-1783.2001
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