Subtype-Specific Translocation of the δ Subtype of Protein Kinase C and Its Activation by Tyrosine Phosphorylation Induced by Ceramide in HeLa Cells

We investigated the functional roles of ceramide, an intracellular lipid mediator, in cell signaling pathways by monitoring the intracellular movement of protein kinase C (PKC) subtypes fused to green fluorescent protein (GFP) in HeLa living cells. C(2)-ceramide but not C(2)-dihydroceramide induced...

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Bibliographische Detailangaben
Hauptverfasser: Kajimoto, Taketoshi, Ohmori, Shiho, Shirai, Yasuhito, Sakai, Norio, Saito, Naoaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86731/
https://ncbi.nlm.nih.gov/pubmed/11238914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1769-1783.2001
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