The Protein Kinase Clk/Sty Directly Modulates SR Protein Activity: Both Hyper- and Hypophosphorylation Inhibit Splicing

The splicing of mammalian mRNA precursors requires both protein phosphorylation and dephosphorylation, likely involving modification of members of the SR protein family of splicing factors. Several kinases have been identified that can phosphorylate SR proteins in vitro, and transfection assays have...

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Detaylı Bibliyografya
Asıl Yazarlar: Prasad, Jayendra, Colwill, Karen, Pawson, Tony, Manley, James L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 1999
Konular:
Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC84694/
https://ncbi.nlm.nih.gov/pubmed/10490636
Etiketler: Etiketle
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