Thymoquinone protects against cardiac mitochondrial DNA loss, oxidative stress, inflammation and apoptosis in isoproterenol-induced myocardial infarction in rats

INTRODUCTION: Myocardial infarction (MI) is an ischemic life-threatening disease with exaggerated oxidative stress state that vigorously damages the cardiomyocyte membrane and subcellular structures, including the vital mitochondrial DNA (mtDNA). The mtDNA is responsible for the proper functionality...

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Gepubliceerd in:Heliyon
Hoofdauteurs: Khalifa, Asmaa A., Rashad, Radwa M., El-Hadidy, Wessam F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322274/
https://ncbi.nlm.nih.gov/pubmed/34355083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e07561
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