TREM-1 inhibition attenuates neuroinflammation via PKC δ/CARD9 signaling pathway after intracerebral hemorrhage in mice

BACKGROUND AND PURPOSE: Intracerebral hemorrhage (ICH) is a devastating subtype of stroke with high mortality and disability. Inflammatory response promotes secondary brain injury after ICH. Triggering receptor expressed on myeloid cells 1 (TREM-1) is a key regulator of inflammation. The aim of this...

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Publicado no:Stroke
Main Authors: Lu, Qin, Liu, Rui, Sherchan, Prativa, Ren, Reng, He, Wei, Fang, Yuanjian, Huang, Yi, Shi, Hui, Tang, Lihui, Yang, Shuxu, Zhang, John H., Tang, Jiping
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321132/
https://ncbi.nlm.nih.gov/pubmed/33947214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.120.032736
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