Long-term ovarian hormone deprivation alters functional connectivity, brain neurochemical profile and white matter integrity in the Tg2576 amyloid mouse model of Alzheimer’s disease

Premenopausal bilateral ovariectomy is considered to be one of the risk factors of Alzheimer’s disease (AD). However, the underlying mechanisms remain unclear. Here, we aimed to investigate long-term neurological consequences of ovariectomy in a rodent AD model, TG2576 (TG), and wild-type mice (WT)...

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書誌詳細
出版年:Neurobiol Aging
主要な著者: Kara, Firat, Belloy, Michael E., Voncken, Rick, Sarwari, Zahra, Garima, Yadav, Anckaerts, Cynthia, Langbeen, An, Leysen, Valerie, Shah, Disha, Jacobs, Jules, Hamaide, Julie, Bols, Peter, Van Audekerke, Johan, Daans, Jasmijn, Guglielmetti, Caroline, Kantarci, Kejal, Prevot, Vincent, Roßner, Steffen, Ponsaerts, Peter, Van der Linden, Annemie, Verhoye, Marleen
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312737/
https://ncbi.nlm.nih.gov/pubmed/33765427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2021.02.011
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