Long-term ovarian hormone deprivation alters functional connectivity, brain neurochemical profile and white matter integrity in the Tg2576 amyloid mouse model of Alzheimer’s disease

Premenopausal bilateral ovariectomy is considered to be one of the risk factors of Alzheimer’s disease (AD). However, the underlying mechanisms remain unclear. Here, we aimed to investigate long-term neurological consequences of ovariectomy in a rodent AD model, TG2576 (TG), and wild-type mice (WT)...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Neurobiol Aging
Autori principali: Kara, Firat, Belloy, Michael E., Voncken, Rick, Sarwari, Zahra, Garima, Yadav, Anckaerts, Cynthia, Langbeen, An, Leysen, Valerie, Shah, Disha, Jacobs, Jules, Hamaide, Julie, Bols, Peter, Van Audekerke, Johan, Daans, Jasmijn, Guglielmetti, Caroline, Kantarci, Kejal, Prevot, Vincent, Roßner, Steffen, Ponsaerts, Peter, Van der Linden, Annemie, Verhoye, Marleen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312737/
https://ncbi.nlm.nih.gov/pubmed/33765427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2021.02.011
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi