De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation

Structural variants (SVs) may play important roles in human adaptation to extreme environments such as high altitude but have been under-investigated. Here, combining long-read sequencing with multiple scaffolding techniques, we assembled a high-quality Tibetan genome (ZF1), with a contig N50 length...

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Detalhes bibliográficos
Publicado no:Natl Sci Rev
Main Authors: He, Yaoxi, Lou, Haiyi, Cui, Chaoying, Deng, Lian, Gao, Yang, Zheng, Wangshan, Guo, Yongbo, Wang, Xiaoji, Ning, Zhilin, Li, Jun, Li, Bin, Bai, Caijuan, Liu, Shiming, Wu, Tianyi, Xu, Shuhua, Qi, Xuebin, Su, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288928/
https://ncbi.nlm.nih.gov/pubmed/34692055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwz160
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