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Combined Analysis of the Moderating Effect of a GRIK1 Polymorphism on the Effects of Topiramate for Treating Alcohol Use Disorder

BACKGROUND: In an initial study, we reported that topiramate reduced heavy drinking among individuals who sought to reduce their drinking and that the effect was moderated by a single nucleotide polymorphism (SNP; rs2832407) in GRIK1, which encodes the kainate GluK1 receptor subunit (Kranzler et al....

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Detalhes bibliográficos
Publicado no:Drug Alcohol Depend
Main Authors: Kranzler, Henry R., Hartwell, Emily E., Feinn, Richard, Pond, Timothy, Witkiewitz, Katie, Gelernter, Joel, Crist, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282735/
https://ncbi.nlm.nih.gov/pubmed/34049101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2021.108762
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