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Acute pre-operative ibuprofen improves cognition in a rat model for postoperative cognitive dysfunction
BACKGROUND: Inflammation is considered a key factor in the development of postoperative cognitive dysfunction (POCD). Therefore, we hypothesized that pre-operative anti-inflammatory treatment with ibuprofen would inhibit POCD in our rat-model. METHODS: Male Wistar rats of 3 or 23 months old received...
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| Publicado no: | J Neuroinflammation |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8265047/ https://ncbi.nlm.nih.gov/pubmed/34238316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02206-y |
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