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First-in-human evaluation of [(11)C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain
PURPOSE: This study assessed whether the newly developed PET radioligand [(11)C]PS13, which has shown excellent in vivo selectivity in previous animal studies, could be used to quantify constitutive levels of cyclooxygenase-1 (COX-1) in healthy human brain. METHODS: Brain test-retest scans with conc...
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| 出版年: | Eur J Nucl Med Mol Imaging |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8261645/ https://ncbi.nlm.nih.gov/pubmed/32399622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-04855-2 |
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