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Identifying patients eligible for PARP inhibitor treatment: from NGS-based tests to 3D functional assays

Within the past few years, poly (ADP-ribose) polymerase inhibitors (PARPi) have been added to the standard of care for cancer patients, mainly for those exhibiting specific genomic alterations in the homologous recombination (HR) pathway. Until now, patients who are eligible to receive PARPi have be...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Morice, Pierre-Marie, Coquan, Elodie, Weiswald, Louis-Bastien, Lambert, Bernard, Vaur, Dominique, Poulain, Laurent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8257604/
https://ncbi.nlm.nih.gov/pubmed/33767416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01295-z
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