Loss of p21-activated kinase Mbt/PAK4 causes Parkinson-like phenotypes in Drosophila

Parkinson's disease (PD) provokes bradykinesia, resting tremor, rigidity and postural instability, and also non-motor symptoms such as depression, anxiety, sleep and cognitive impairments. Similar phenotypes can be induced in Drosophila melanogaster through modification of PD-relevant genes or...

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Bibliografiske detaljer
Udgivet i:Dis Model Mech
Main Authors: Pütz, Stephanie M., Kram, Jette, Rauh, Elisa, Kaiser, Sophie, Toews, Romy, Lueningschroer-Wang, Yi, Rieger, Dirk, Raabe, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246267/
https://ncbi.nlm.nih.gov/pubmed/34125184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.047811
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