Formulation of Chewable Tablets Containing Carbamazepine-β-cyclodextrin Inclusion Complex and F-Melt Disintegration Excipient. The Mathematical Modeling of the Release Kinetics of Carbamazepine

Due to its low solubility, carbamazepine (CBZ) exhibits slow and incomplete release in the gastrointestinal tract and, hence, variable pharmacokinetics and pharmacodynamic effect. Lots of methods have been devised to improve its solubility, the large number of proposed solutions being a sign that th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Pharmaceutics
Prif Awduron: Musuc, Adina Magdalena, Anuta, Valentina, Atkinson, Irina, Sarbu, Iulian, Popa, Vlad Tudor, Munteanu, Cornel, Mircioiu, Constantin, Ozon, Emma Adriana, Nitulescu, George Mihai, Mitu, Mirela Adriana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235681/
https://ncbi.nlm.nih.gov/pubmed/34205629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060915
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