Formulation of Chewable Tablets Containing Carbamazepine-β-cyclodextrin Inclusion Complex and F-Melt Disintegration Excipient. The Mathematical Modeling of the Release Kinetics of Carbamazepine

Due to its low solubility, carbamazepine (CBZ) exhibits slow and incomplete release in the gastrointestinal tract and, hence, variable pharmacokinetics and pharmacodynamic effect. Lots of methods have been devised to improve its solubility, the large number of proposed solutions being a sign that th...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Musuc, Adina Magdalena, Anuta, Valentina, Atkinson, Irina, Sarbu, Iulian, Popa, Vlad Tudor, Munteanu, Cornel, Mircioiu, Constantin, Ozon, Emma Adriana, Nitulescu, George Mihai, Mitu, Mirela Adriana
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235681/
https://ncbi.nlm.nih.gov/pubmed/34205629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060915
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