Formulation of Chewable Tablets Containing Carbamazepine-β-cyclodextrin Inclusion Complex and F-Melt Disintegration Excipient. The Mathematical Modeling of the Release Kinetics of Carbamazepine

Due to its low solubility, carbamazepine (CBZ) exhibits slow and incomplete release in the gastrointestinal tract and, hence, variable pharmacokinetics and pharmacodynamic effect. Lots of methods have been devised to improve its solubility, the large number of proposed solutions being a sign that th...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Musuc, Adina Magdalena, Anuta, Valentina, Atkinson, Irina, Sarbu, Iulian, Popa, Vlad Tudor, Munteanu, Cornel, Mircioiu, Constantin, Ozon, Emma Adriana, Nitulescu, George Mihai, Mitu, Mirela Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235681/
https://ncbi.nlm.nih.gov/pubmed/34205629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060915
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