A Compositional Model to Predict the Aggregated Isotope Distribution for Average DNA and RNA Oligonucleotides

Structural modifications of DNA and RNA molecules play a pivotal role in epigenetic and posttranscriptional regulation. To characterise these modifications, more and more MS and MS/MS- based tools for the analysis of nucleic acids are being developed. To identify an oligonucleotide in a mass spectru...

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Bibliographic Details
Published in:Metabolites
Main Authors: Agten, Annelies, Prostko, Piotr, Geubbelmans, Melvin, Liu, Youzhong, De Vijlder, Thomas, Valkenborg, Dirk
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234063/
https://ncbi.nlm.nih.gov/pubmed/34207227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11060400
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