Delineation of Molecular Lesions in Acute Myeloid Leukemia Patients at Diagnosis: Integrated Next Generation Sequencing and Cytogenomic Studies

Acute myeloid leukemia (AML) is a heterogeneous disorder characterized by a wide range of genetic defects. Cytogenetics, molecular and genomic technologies have proved to be helpful for deciphering the mutational landscape of AML and impacted clinical practice. Forty-eight new AML patients were inve...

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Veröffentlicht in:Genes (Basel)
Hauptverfasser: Papuc, Sorina Mihaela, Erbescu, Alina, Cisleanu, Diana, Ozunu, Diana, Enache, Cristina, Dumitru, Ion, Lupoaia Andrus, Elena, Gaman, Mihaela, Popov, Viola Maria, Dobre, Maria, Stanca, Oana, Angelescu, Silvana, Berbec, Nicoleta, Colita, Andrei, Vladareanu, Ana-Maria, Bumbea, Horia, Arghir, Aurora
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229708/
https://ncbi.nlm.nih.gov/pubmed/34070898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060846
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