The equilibrative nucleoside transporter ENT1 is critical for nucleotide homeostasis and optimal erythropoiesis

The tight regulation of intracellular nucleotides is critical for the self-renewal and lineage specification of hematopoietic stem cells (HSCs). Nucleosides are major metabolite precursors for nucleotide biosynthesis and their availability in HSCs is dependent on their transport through specific mem...

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Veröffentlicht in:Blood
Hauptverfasser: Mikdar, Mahmoud, González-Menéndez, Pedro, Cai, Xiaoli, Zhang, Yujin, Serra, Marion, Dembele, Abdoul K., Boschat, Anne-Claire, Sanquer, Sylvia, Chhuon, Cerina, Guerrera, Ida Chiara, Sitbon, Marc, Hermine, Olivier, Colin, Yves, Le Van Kim, Caroline, Kinet, Sandrina, Mohandas, Narla, Xia, Yang, Peyrard, Thierry, Taylor, Naomi, Azouzi, Slim
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2021
Schlagworte:
Red Cells, Iron, and Erythropoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225918/
https://ncbi.nlm.nih.gov/pubmed/33690842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020007281
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