Yüklüyor......

Insights into the substrate binding mechanism of SULT1A1 through molecular dynamics with excited normal modes simulations

Sulfotransferases (SULTs) are phase II drug-metabolizing enzymes catalyzing the sulfoconjugation from the co-factor 3′-phosphoadenosine 5′-phosphosulfate (PAPS) to a substrate. It has been previously suggested that a considerable shift of SULT structure caused by PAPS binding could control the capab...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Dudas, Balint, Toth, Daniel, Perahia, David, Nicot, Arnaud B., Balog, Erika, Miteva, Maria A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222352/
https://ncbi.nlm.nih.gov/pubmed/34162941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92480-w
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!