Discovery of a Small Side Cavity in Sphingosine Kinase 2 that Enhances Inhibitor Potency and Selectivity

Παρόμοια τεκμήρια

• Transforming Sphingosine Kinase 1 Inhibitors into Dual and Sphingosine Kinase 2 Selective Inhibitors: Design, Synthesis, and In Vivo Activity
  ανά: Childress, Elizabeth S., κ.ά.
  Έκδοση: (2017)
• Structure–Activity Relationship Studies and in Vivo Activity of Guanidine-Based Sphingosine Kinase Inhibitors: Discovery of SphK1- and SphK2-Selective Inhibitors
  ανά: Patwardhan, Neeraj N., κ.ά.
  Έκδοση: (2015)
• Structure–Activity Relationship Studies and Molecular Modeling of Naphthalene-Based Sphingosine Kinase 2 Inhibitors
  ανά: Congdon, Molly D., κ.ά.
  Έκδοση: (2016)
• Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors
  ανά: Raje, Mithun R., κ.ά.
  Έκδοση: (2011)
• Probing the Substitution Pattern of Indole-Based Scaffold Reveals Potent and Selective Sphingosine Kinase 2 Inhibitors
  ανά: Congdon, Molly, κ.ά.
  Έκδοση: (2020)