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In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23

Fibroblast growth factor 23 (FGF23) is a hormone secreted from fully differentiated osteoblasts and osteocytes that inhibits phosphate reabsorption by kidney proximal tubules. The full-length (i.e., intact) protein mediates FGF23 endocrine functions, while endoproteolytic cleavage at a consensus cle...

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Publicat a:Front Endocrinol (Lausanne)
Autors principals: Al Rifai, Omar, Susan-Resiga, Delia, Essalmani, Rachid, Creemers, John W. M., Seidah, Nabil G., Ferron, Mathieu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213403/
https://ncbi.nlm.nih.gov/pubmed/34149625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.690681
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