Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics

3D culture of cells in designer biomaterial matrices provides a biomimetic cellular microenvironment and can yield critical insights into cellular behaviours not available from conventional 2D cultures. Hydrogels with dynamic properties, achieved by incorporating either degradable structural compone...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Yang, Boguang, Wei, Kongchang, Loebel, Claudia, Zhang, Kunyu, Feng, Qian, Li, Rui, Wong, Siu Hong Dexter, Xu, Xiayi, Lau, Chunhon, Chen, Xiaoyu, Zhao, Pengchao, Yin, Chao, Burdick, Jason A., Wang, Yi, Bian, Liming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192531/
https://ncbi.nlm.nih.gov/pubmed/34112772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23120-0
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