Acute lymphoblastic leukemia-derived exosome inhibits cytotoxicity of natural killer cells by TGF-β signaling pathway

This study was conducted to explore whether acute lymphoblastic leukemia (ALL)-derived exosomes affect natural killer (NK) cells. Exosomes were isolated and identified from Jurkat cells and co-cultured with NK cells. Then, the cytotoxicity, viability, and release of perforin and granzyme B in NK92-M...

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Detalhes bibliográficos
Publicado no:3 Biotech
Main Authors: Yu, Huijun, Huang, Tingting, Wang, Daming, Chen, Lei, Lan, Xi, Liu, Xintong, Chen, Keyan, He, Haihong, Li, Shaobo, Zhou, Yiwen, Xie, Jiansheng
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178429/
https://ncbi.nlm.nih.gov/pubmed/34109098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-021-02817-5
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