HIV-1 uncoating by release of viral cDNA from capsid-like structures in the nucleus of infected cells

HIV-1 replication commences inside the cone-shaped viral capsid, but timing, localization, and mechanism of uncoating are under debate. We adapted a strategy to visualize individual reverse-transcribed HIV-1 cDNA molecules and their association with viral and cellular proteins using fluorescence and...

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Detalhes bibliográficos
Publicado no:eLife
Principais autores: Müller, Thorsten G, Zila, Vojtech, Peters, Kyra, Schifferdecker, Sandra, Stanic, Mia, Lucic, Bojana, Laketa, Vibor, Lusic, Marina, Müller, Barbara, Kräusslich, Hans-Georg
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169111/
https://ncbi.nlm.nih.gov/pubmed/33904396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64776
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