Cell Adhesion Molecules are Upregulated and May Drive Inflammation in Chronic Rhinosinusitis with Nasal Polyposis

PURPOSE: Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly characterized by eosinophil- and T helper 2 cell (Th2)-biased inflammation. Integrins and intercellular adhesion molecules (ICAMs) are superfamilies of cell adhesion molecules (CAMs) that facilitate the recruitment and traff...

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Veröffentlicht in:J Asthma Allergy
Hauptverfasser: Blight, Brennan J, Gill, Amarbir S, Sumsion, Jorgen S, Pollard, Chelsea E, Ashby, Shaelene, Oakley, Gretchen M, Alt, Jeremiah A, Pulsipher, Abigail
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2021
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166329/
https://ncbi.nlm.nih.gov/pubmed/34079296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JAA.S307197
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