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Subcellular distribution of ezrin/radixin/moesin and their roles in the cell surface localization and transport function of P-glycoprotein in human colon adenocarcinoma LS180 cells

The ezrin/radixin/moesin (ERM) family proteins act as linkers between the actin cytoskeleton and P-glycoprotein (P-gp) and regulate the plasma membrane localization and functionality of the latter in various cancer cells. Notably, P-gp overexpression in the plasma membrane of cancer cells is a princ...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Kobori, Takuro, Tameishi, Mayuka, Tanaka, Chihiro, Urashima, Yoko, Obata, Tokio
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8112653/
https://ncbi.nlm.nih.gov/pubmed/33974673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0250889
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