Serum creatine kinase and creatinine in adult spinal muscular atrophy under nusinersen treatment

OBJECTIVE: To determine whether serum creatine kinase activity (CK) and serum creatinine concentration (Crn) are prognostic and predictive biomarkers for disease severity, disease progression, and nusinersen treatment effects in adult patients with 5q‐associated spinal muscular atrophy (SMA). METHOD...

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發表在:Ann Clin Transl Neurol
Main Authors: Freigang, Maren, Wurster, Claudia D., Hagenacker, Tim, Stolte, Benjamin, Weiler, Markus, Kamm, Christoph, Schreiber‐Katz, Olivia, Osmanovic, Alma, Petri, Susanne, Kowski, Alexander, Meyer, Thomas, Koch, Jan C., Cordts, Isabell, Deschauer, Marcus, Lingor, Paul, Aust, Elisa, Petzold, Daniel, Ludolph, Albert C., Falkenburger, Björn, Hermann, Andreas, Günther, René
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2021
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Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108420/
https://ncbi.nlm.nih.gov/pubmed/33792208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51340
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