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Cell-type and fetal-sex-specific targets of prenatal alcohol exposure in developing mouse cerebral cortex

Prenatal alcohol exposure (PAE) results in cerebral cortical dysgenesis. Single-cell RNA sequencing was performed on murine fetal cerebral cortical cells from six timed pregnancies, to decipher persistent cell- and sex-specific effects of an episode of PAE during early neurogenesis. We found, in an...

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Udgivet i:iScience
Main Authors: Salem, Nihal A., Mahnke, Amanda H., Konganti, Kranti, Hillhouse, Andrew E., Miranda, Rajesh C.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8105653/
https://ncbi.nlm.nih.gov/pubmed/33997709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102439
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