Cyclophilin A induces macrophage apoptosis and enhances atherosclerotic lesions in high‐fat diet‐fed hyperglycemic rabbits

Macrophage apoptosis is a key contributor to the progression of atherosclerosis. Cyclophilin A, a monocyte secretory protein associated with the initiation of atherosclerosis has an inherent nuclease activity. This study reports the mechanism by which cyclophilin A causes apoptosis of macrophages an...

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Udgivet i:FASEB Bioadv
Main Authors: Anandan, Vinitha, Thankayyan Retnabai, Santhosh Kumar, Jaleel, Abdul, Thulaseedharan, Thushara, Mullasari, Ajit, Pillai, M. Radhakrishna, Kartha, Cheranellore Chandrasekharan, Ramachandran, Surya
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103716/
https://ncbi.nlm.nih.gov/pubmed/33977232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2020-00135
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