Glucocorticoid receptor modulators decrease alcohol self-administration in male rats

Alcohol use disorder (AUD) is associated with the dysregulation of brain stress and reward systems, including glucocorticoid receptors (GRs). The mixed glucocorticoid/progesterone receptor antagonist mifepristone and selective GR antagonist CORT113176 have been shown to selectively reduce alcohol co...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: McGinn, M. Adrienne, Tunstall, Brendan J., Schlosburg, Joel E., Gregory-Flores, Adriana, George, Olivier, de Guglielmo, Giordano, Mason, Barbara J., Hunt, Hazel J., Koob, George F., Vendruscolo, Leandro F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099171/
https://ncbi.nlm.nih.gov/pubmed/33647278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2021.108510
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