Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos

Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from Aconitum plants, is widely used in traditional herbal medicine to treat various diseases. Emerging evidence indicates that AC has attracted great interest for its wide cardiotoxicity and neurotoxicity. However, the toxic effec...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Xia, Qing, Gao, Shuo, Rapael Gnanamuthu, Samuel Rajendran, Zhuang, Kaiyan, Song, Zhenzhen, Zhang, Yun, Wang, Xue, Tu, Pengfei, Li, Jianheng, Liu, Kechun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097150/
https://ncbi.nlm.nih.gov/pubmed/33967776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.642480
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi