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Improving therapeutic potential of non-viral minimized DNA vectors

The tragic deaths of three patients in a recent AAV-based X-linked myotubular myopathy clinical trial highlight once again the pressing need for safe and reliable gene delivery vectors. Non-viral minimized DNA vectors offer one possible way to meet this need. Recent pre-clinical results with minimiz...

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Detalhes bibliográficos
Publicado no:Cell Gene Ther Insights
Main Authors: Arévalo-Soliz, Lirio M, Hardee, Cinnamon L, Fogg, Jonathan M, Corman, Nathan R, Noorbakhsh, Cameron, Zechiedrich, Lynn
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095377/
https://ncbi.nlm.nih.gov/pubmed/33953961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18609/cgti.2020.163
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