Protective Role of Transduced Tat-Thioredoxin1 (Trx1) against Oxidative Stress-Induced Neuronal Cell Death via ASK1-MAPK Signal Pathway

Oxidative stress plays a crucial role in the development of neuronal disorders including brain ischemic injury. Thioredoxin 1 (Trx1), a 12 kDa oxidoreductase, has anti-oxidant and anti-apoptotic functions in various cells. It has been highly implicated in brain ischemic injury. However, the protecti...

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Publicado no:Biomol Ther (Seoul)
Main Authors: Yeo, Eun Ji, Eum, Won Sik, Yeo, Hyeon Ji, Choi, Yeon Joo, Sohn, Eun Jeong, Kwon, Hyun Jung, Kim, Dae Won, Kim, Duk-Soo, Cho, Sung-Woo, Park, Jinseu, Han, Kyu Hyung, Lee, Keun Wook, Park, Jong Kook, Shin, Min Jea, Choi, Soo Young
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2021
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094070/
https://ncbi.nlm.nih.gov/pubmed/33436533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.154
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