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Allostery of atypical modulators at oligomeric G protein-coupled receptors
Many G protein-coupled receptors (GPCRs) are therapeutic targets, with most drugs acting at the orthosteric site. Some GPCRs also possess allosteric sites, which have become a focus of drug discovery. In the M(2) muscarinic receptor, allosteric modulators regulate the binding and functional effects...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8085029/ https://ncbi.nlm.nih.gov/pubmed/33927236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88399-x |
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