A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2

Mutations and transient conformational movements of the receptor binding domain (RBD) that make neutralizing epitopes momentarily unavailable present immune escape routes for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To mitigate viral escape, we developed a cocktail of neutralizi...

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Veröffentlicht in:Natl Sci Rev
Hauptverfasser: Zhang, Li, Cao, Lei, Gao, Xing-Su, Zheng, Bin-Yang, Deng, Yong-Qiang, Li, Jing-Xin, Feng, Rui, Bian, Qian, Guo, Xi-Ling, Wang, Nan, Qiu, Hong-Ying, Wang, Lei, Cui, Zhen, Ye, Qing, Chen, Geng, Lu, Kui-Kui, Chen, Yin, Chen, Yu-Tao, Pan, Hong-Xing, Yu, Jiaping, Yao, Wenrong, Zhu, Bao-Li, Chen, Jianping, Liu, Yong, Qin, Cheng-Feng, Wang, Xiangxi, Zhu, Feng-Cai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
RESEARCH ARTICLE
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083607/
https://ncbi.nlm.nih.gov/pubmed/34676098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwab053
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