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Neddylation is required for presynaptic clustering of mGlu7 and maturation of presynaptic terminals

Neddylation is a posttranslational modification in which NEDD8 is conjugated to a target substrate by cellular processes similar to those involved in ubiquitination. Recent studies have identified PSD-95 and cofilin as substrates for neddylation in the brain and have shown that neddylation modulates...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Mol Med
Hauptverfasser: Kang, Minji, Lee, DoEun, Song, Jae-man, Park, Sunha, Park, Da-ha, Lee, Sanghyeon, Suh, Young Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080653/
https://ncbi.nlm.nih.gov/pubmed/33767338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-021-00585-z
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