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Mangiferin Inhibits Apoptosis in Doxorubicin-Induced Vascular Endothelial Cells via the Nrf2 Signaling Pathway

Doxorubicin increases endothelial permeability, hence increasing cardiomyocytes’ exposure to doxorubicin (DOX) and exposing myocytes to more immediate damage. Reactive oxygen species are major effector molecules of doxorubicin’s activity. Mangiferin (MGN) is a xanthone derivative that consists of C-...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Ismail, Mohammad Bani, Rajendran, Peramaiyan, AbuZahra, Hamad Mohammed, Veeraraghavan, Vishnu Priya
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073066/
https://ncbi.nlm.nih.gov/pubmed/33923922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084259
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