Novel brd4 inhibitors with a unique scaffold exhibit antitumor effects

Since bromodomain containing 4 (brd4) has been considered as a prominent cancer target, numerous attempts have been made to develop potent brd4 bromodomain inhibitors. The present study provided a novel chemical scaffold which inhibited brd4 activity. Mid-throughput screening against brd4 bromodomai...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Kim, Young Hun, Kim, Minsung, Kim, Ji Eun, Yoo, Miyoun, Lee, Heung Kyoung, Lee, Chong Ock, Yoo, Minjin, Jung, Kwan-Young, Kim, Yeongrin, Choi, Sang Un, Park, Chi Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063330/
https://ncbi.nlm.nih.gov/pubmed/33907583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12734
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