Sodium arsenite induces spatial learning and memory impairment associated with oxidative stress and activates the Nrf2/PPARγ pathway against oxidative injury in mice hippocampus

Arsenic (As) is a ubiquitous environmental and industrial toxin with known correlates of oxidative stress and cognitive deficits in the brain. Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcriptional factor that represents a central cellular antioxidant defense mechanism and transcrib...

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Veröffentlicht in:Toxicol Res (Camb)
Hauptverfasser: Xiong, Liang, Huang, Jinyu, Gao, Ying, Gao, Yanfang, Wu, Chunmei, He, Shengfa, Zou, Lijun, Yang, Dongmei, Han, Yuhao, Yuan, Qiong, Zheng, Zuobing, Hu, Gonghua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
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Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8045596/
https://ncbi.nlm.nih.gov/pubmed/33884178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxres/tfab007
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